Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy ...

A newly mapped step in DNA replication suggests that strand separation begins at a precise junction between two helicase ...

When a virus enters a cell, its top priority is to replicate its genome rapidly, creating new viruses to infect elsewhere.

Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent. This means that, millions of times a day, a biochemical wonder takes ...

A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...

The dangers of antibiotic overuse have become increasingly clear in recent decades. Excessive use accelerates the evolution of bacterial resistance to antibiotics, raising the alarming prospect of ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that ...

Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a ...

Real image of DNA molecules being copied in human cells, visualized by immunofluorescence microscopy. The yellow arrows mark where replication begins, and the white arrows indicate the direction in ...