Every time a cell divides, it must accurately copy and distribute its DNA between two new cells. However, in some cases, ...
Our DNA is under constant threat. Chemicals, radiation and the everyday errors of cell division all damage it, and if left ...
Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy ...
Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes ...
Deep learning approaches have transformed how scientists predict the activity and function of DNA sequences in the genome. A ...
Every time a cell divides, it must accurately copy and distribute its DNA between two new cells. However, in some cases, ...
Scientists have exploited a peculiar CRISPR enzyme so that it fights cancer by shredding the DNA in cancer cells, causing ...
A new study finds that mitochondria in our brain cells frequently fling their DNA into the cells' nucleus, where the mitochondrial DNA integrates into chromosomes, possibly causing harm. As direct ...
The cancer drugs called PARP inhibitors have a puzzling reputation: even though they are treatment mainstays for multiple forms of cancer, they can damage cancer-killing T cells and disrupt the ...
Michael Haffner, MD, PhD, and Kevin Cheung, MD, have recently been awarded multi-year research grants from the V Foundation ...
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