Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes ...
A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...
Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...
Add Yahoo as a preferred source to see more of our stories on Google. Double-strand breaks in DNA can be deadly. Victor Golmer/iStock via Getty Images Plus Your DNA is continually damaged by sources ...
Newborn mice neurons can snap both DNA strands to migrate, then repair the breaks within a day. The process may be a normal part of brain development.
You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...
DNA double-strand breaks (DSBs) represent a critical form of damage in which both strands of the DNA helix are severed. If left unrepaired or misrepaired, DSBs can lead to chromosomal translocations, ...
Researchers at King Abdullah University of Science and Technology (KAUST) have developed a new way to add large pieces of ...
Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...